Combine Selenium with CoQ10 for Healthy Aging

A recent groundbreaking clinical study, focused on the effects of selenium and coenzyme Q10 supplements, has sparked interest within the scientific community. This study, titled "Selenoprotein P increases upon selenium and coenzyme Q10 supplementation and is associated with telomere length, quality of life and reduced inflammation and mortality," investigates how these supplements can impact our health and longevity.

The primary focus of this study is on Selenoprotein P (SELENOP), a protein that transports selenium to various tissues and serves as a biomarker of selenium status. Low selenium intake, often due to poor soil content, can decrease quality of life during normal aging. Consequently, enhancing selenium levels in the body through supplements like selenium and coenzyme Q10 can potentially enhance healthy aging. The study explores SELENOP's relationship with various health markers including inflammation, telomere length, quality of life, and mortality.

Study Design

The study was a randomized controlled trial involving 403 elderly participants living in communities with low selenium levels. These individuals were divided into two groups: one group received daily supplements of selenium (200 mcg) and coenzyme Q10 (200 mg), while the other group received a placebo. The participants were monitored over a period of four years to assess the long-term effects of the supplements.

Researchers measured the serum levels of SELENOP at the start of the study and after the four-year intervention period. They used various advanced statistical methods such as T-tests, ANCOVA analyses, and Kaplan-Meier graphs to evaluate the data. The study also investigated the associations between SELENOP levels and biomarkers of inflammation, telomere length, quality of life, and overall mortality.

Furthermore, the study aimed to identify the serum selenium concentration required to achieve saturation levels of SELENOP and GPx3, another important selenium-dependent enzyme. By doing so, researchers hoped to establish a comprehensive understanding of how selenium supplementation can enhance selenium transport and enhance health.

Study Results

The results of the study indicated a significant inverse relationship between initial SELENOP levels and biomarkers of inflammation. Participants with low SELENOP levels at the beginning of the study exhibited higher inflammation markers. Conversely, those with higher SELENOP levels had lower inflammation and better overall health.

At the four-year follow-up, the study found that participants with higher levels of SELENOP experienced longer telomere lengths, which are indicative of slower cellular aging. Additionally, these individuals reported better quality of life and had lower mortality rates compared to those with lower SELENOP levels. These findings suggest that SELENOP is a crucial factor in promoting healthly longevity.

The study also demonstrated that supplements with selenium and coenzyme Q10 effectively increased serum SELENOP levels. This increase in SELENOP was associated with improved selenium bioavailability in the body, ultimately translating into positive health benefits. Notably, the study identified specific serum selenium concentrations required to achieve the desired SELENOP and GPx3 saturation levels, providing valuable guidance for future supplement strategies.

Thrivous Vitality

Based on the findings of this study, it is recommended that individuals consider incorporating selenium and coenzyme Q10 supplements into their daily regimen. These supplements have shown to significantly improve SELENOP levels, which in turn can reduce inflammation, slow down cellular aging, and enhance overall quality of life. For users of Thrivous supplements, this study validates the benefits of including selenium and coenzyme Q10 in their health and wellness routines.

Thrivous develops Vitality Geroprotector to enhance metabolic and cellular function for better aging. Each serving of Vitality provides a clinical dose of selenium and coenzyme Q10. As implied by this study, long-term use of Vitality may help to enhance several biomarkers related to healthy aging. Vitality Geroprotector is available to purchase online now in the Thrivous store.