This Supplement Combo May Decrease Aging Effect of Stress

14 January 2021
Christopher C. Smith
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Cycling

In 2016, researchers from the University of Padova in Italy published a study in the journal Nutrients. It demonstrated that a Mediterranean Diet, combined with a daily supplement of Curcumin and Boswellia Serrata Extract (BSE), has a protective effect against oxidative stress.

Oxidative stress plays a major role in aging and the deterioration of health over time. The reason your mother taught you to eat your vegetables for the antioxidants is that they help combat oxidative stress. Curcumin and BSE are both powerful antioxidants, and Curcumin is anti-inflammatory as well.

The Italian researchers behind the Nutrients study recruited a cohort of 47 male master cyclists — all healthy, high-performance athletes — to participate in the study. The cyclists made a useful study group because regular intensive exercise causes oxidative stress.

That means these cyclists had pretty high baseline levels of the chemical markers the researchers were interested in. In athletes, oxidative stress can cause muscle damage and reduced athletic performance. It can also accumulate in the cells and tissues over time and accelerate age-related decline.

The researchers wanted to see if diet and supplements could reduce the markers of oxidative stress in these athletes’ bodies. So they divided the athletes into two groups:

  • The control group was prescribed a Mediterranean Diet.
  • The treatment group was prescribed both a Mediterranean Diet and a daily supplement.

The supplement was a tablet containing 140 mg of BSE and 10 mg of Curcumin, in a proprietary formula designed for easy cellular absorption. The researchers required all participants to keep a food diary and to return unused pills at the end of the trial, so they could verify compliance.

Blood and urine samples were taken once at the beginning of the trial and once at the end, after 3 months. The blood and urine samples were examined for twelve different potential markers of oxidative stress.

At the end of the study period, both the treatment and control groups exhibited a significant reduction in three of the twelve markers. This suggests that a Mediterranean Diet, by itself, goes a long way toward reducing oxidative stress.

The treatment group also saw statistically significant reductions in two markers compared to the control group. They included a 47% reduction in total Advanced Glycation End-products (AGEs). This suggests that treatment with Curcumin and BSE provides a substantial benefit beyond what a Mediterranean Diet confers.

Advanced Glycation End-products (AGEs) can either be derived from food or produced within the body, especially under conditions of hyperglycemia or oxidative stress. AGEs cause harmful stiffening of tissues, such as skeletal muscle, tendons, joints, bone, heart, arteries, lungs, and skin. They accumulate in cells and skeletal muscle tissue as we age.

Levels of AGEs in older adults seem to predict an earlier death. So a safe supplement that reduces levels of AGEs could have powerful anti-aging benefits.

Both Curcumin and BSE had previously shown promise for reducing AGEs in vitro and in animal studies. But the Nutrients study is the first to document this effect in humans.

Thrivous Tenacity Arthroprotector contains both 500 mg of Turmeric Rhizome Extract (95% Curcumin) and 100 mg of Boswellia Serrata Resin Extract. Maybe you’re a master cyclist looking to maximize athletic performance. Or maybe you're just a regular person looking to stave off age-related decline. Either way, Tenacity can offer you valuable protection against the chemical effects of stress.

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