Welcome to Thrivous!

Promote Restorative Sleep with Thrivous Serenity

18 June 2022
Jae Haroldsen


In our hectic world, where everyone wants to do more and be more, there is one thing that significantly improves energy, focus, cognition, memory, and mood. And in addition, it supports healthy aging.

In some ways, our bodies can be compared to a computer. Rebooting an electronic device that is acting weird can be almost magical. A full night’s sleep (7-8 hours for the average adult) does the same thing for our minds and bodies. We may think of sleep as rest, but it is actually a reboot.

During sleep, almost every system in the body resets. Neuroscientist Dr. Merrill Mitler reports that “sleep services all aspects of our body.” It works on a molecular level to provide healthy gains by affecting cardiovascular and immune health, stress and growth hormones, cognitive reasoning, productivity, and even appetite.

Lack of sufficient sleep is linked to age-related cognitive decline, increased anxiety and depression, obesity, heart disease, and an increased risk of illness.

Getting sufficient high-quality sleep might be easier said than done. Thrivous Serenity has been clinically designed to naturally support relaxation, enhance restorative sleep, and improve next-day cognition and focus.

Clinical Formulation

It is often hard to calm and relax the mind at bedtime. Nothing is worse than lying in bed, knowing you really need sleep, but your mind is spinning. Or even more disturbing is drifting off quickly to only awaken in a couple of hours and not be able to go back to sleep.

To promote relaxation, Thrivous Serenity contains ashwagandha and L-theanine. To promote falling and staying asleep, Thrivous Serenity includes magnesium glycinate and melatonin.

Ingredients for Relaxation

Ashwagandha Root Extract (KSM-66® Withanolide) 300 mg

Ashwagandha is a clinically proven adaptogen used in traditional Indian medicine. Adaptogens are natural herbs that help normalize the body’s reaction to stress. Clinical trials show ashwagandha supplementation promotes a notable and highly consistent calming effect on people with stress, including stress from social situations.

Stress is common in both mine and my husband’s family. When my daughter entered her junior year of high school, she asked if she could start taking something to take the edge off her relentless stress. Fortunately, I discovered this clinical trial that showed a 27.9% average reduction in participants’ blood serum cortisol levels after 60 days of supplementing with ashwagandha root extract (300 mg) -- our primary stress hormone is cortisol.

Like most substances used to combat stress, ashwagandha requires time to accumulate in the system. Within a month of starting ashwagandha supplementation, my daughter reported feeling like she could better concentrate and explore solutions rather than fighting negative feelings. It is a great win for her without the side effects associated with other options.

A 2019 study showed ashwagandha reduced serum cortisol levels and perceived stress in participants while improving sleep quality. These results were seen in participants taking either 250 mg or 600 mg of ashwagandha daily over those taking a placebo.

KSM-66® Withanolide Ashwaganda has the highest bioavailability and concentration. It is the most clinically studied ashwagandha on the market. suggests 600 mg daily may improve sleep. The effectiveness of long-term ashwagandha use has not been well studied. Most studies report ashwagandha is well tolerated.

L-Theanine 200 mg

L-Theanine is a plant-based amino acid that has been clinically shown to help calm, relax, and focus the mind. It crosses the blood-brain barrier to increase brain activity in the alpha frequency range. Alpha-band oscillations calm brain activity to improve attention and processing.

Studies indicate L-Theanine has a notable and highly consistent relaxation effect, improving reaction time and performance, especially for highly stressed people. My daughter loves taking L-Theanine before stress-inducing activities such as tests, auditions, presentations, and social situations.

As a sleep aid, L-Theanine appears to have stress reducing effects. The relaxed calmness generated from increased alpha wave activity helps shut down the mind to initiate high-quality sleep. One study suggests “200 mg of L-Theanine taken before bed may support improved sleep quality not by sedation but by anxiolysis.”

Another study found taking 400 mg of L-Theanine (200 mg morning dose and 200 mg afternoon dose) significantly improved sleep percentages and efficacy scores in boys who were experiencing difficulty focusing.

Ingredients for Sleep

Magnesium 150 mg (Magnesium Glycinate 600 mg)

Magnesium is an essential mineral involved in hundreds of enzyme processes. Unfortunately, the average American diet avoids magnesium-rich foods such s dark green leafy vegetables, seeds, legumes, nuts, and whole grains. According to the 2015-2020 US Dietary Survey, 61% of adults consume less than the estimated average requirement for magnesium.

Among other things magnesium may help:

  • Relax muscles
  • Enhance sleep
  • Lower blood pressure in healthy adults
  • Promote anti-aging electrical and hormonal activity during sleep. 

A small study involving elderly adults found magnesium supplementation may help increase the amount of time spent in the slow-wave sleep cycle. Energy is restored in this cycle by improving sleep quality and memory processing and reducing cortisol secretion.

In addition, low blood serum magnesium levels are often associated with conditions linked to chronic inflammatory stress markers.

Standard magnesium supplement dosages range from 250 to 450 mg per day. As a caution, the upper tolerable intake level (UTIL) is set at 350 mg per day. The UTIL for magnesium is the highest dose not associated with diarrhea symptoms.

Thrivous Serenity incorporates magnesium in the form of highly bioavailable magnesium glycinate. Magnesium glycinate may provide additional nootropic benefits because the compound is roughly 20% magnesium and 80% glycine (an amino acid). Glycine may also support restorative sleep and fight fatigue.

Melatonin 5 mg

Melatonin is a bioidentical hormone that induces and regulates sleep. It provides the following benefits:

  • Enhances mental and physical performance
  • Supports healthy gastrointestinal function
  • Normalizes irregular sleep patterns

Melatonin also may help reduce blood pressure and slow age-related cognitive impairment due to its ability to neutralize free radicals. However, its primary hormone purpose is to decrease the amount of time it takes to fall asleep. 

Melatonin levels naturally decrease with age. Low melatonin levels disturb sleep cycles and can be associated with insomnia. A study of prolonged-release melatonin supplementation (2 mg) taken nightly for three weeks to six months significantly improved how long it took for participants to fall asleep, their sleep quality, and hence, their reported quality of life.

The study indicated the melatonin supplement was well tolerated with “no withdrawal symptoms or rebound insomnia detected.” Though all age groups benefited from melatonin supplementation, those over 55 saw the most favorable gains in reducing the amount of time to fall asleep.

A study involving postmenopausal women with various physical symptoms found supplementing with melatonin (3 mg in the morning and 5 mg at bedtime) reduced body mass index (BMI) on average from 30.9 to 28.1 and significantly improved menopausal symptoms.

Science, Quality, and Transparency

Thrivous builds its brand on educated consumer trust. We formulate our supplements based on the latest clinical research and provide links for you to see that research. We want you to have the information you need to make the best decision for your health and future.

We provide open source formulas for each product and incorporate the highest quality ingredients. In addition, Thrivous supplements are passed through a series of third-party laboratory tests to ensure the purity, strength, and safety of our products.

With Thrivous supplements, you get the most well-studied ingredients at clinical dosages.

Get on top of your day, be more energized, clear your mind, and be more productive. Thrivous Serenity Nightly Nootropic calms and relaxes to promote restorative sleep to reset and reboot. Try it today!

Buy Serenity Nightly Nootropic

More Articles

Read more articles at Thrivous, the human enhancement company. You can browse recent articles in Thrivous Views. See other Nootropics articles. Or check out an article below.